Table 2. Effect of SO-AgNPs on hematological parameters in the rat sub-acute toxicity assessment.
|
Units |
Control |
3mg/kg |
10mg/kg |
30mg/kg |
p value |
|
|
Red Blood Cells |
106/µL |
8.0 ± 0.18 |
8.70 ± 0.20 |
8.37 ± 0.12 |
7.89 ± 0.39 |
0.1419 |
|
Hemoglobin |
g/dl |
14.0 ± 0.10 |
13.53 ± 0.13 |
13.80 ± 0.12 |
13.37± 0.29 |
0.097 |
|
% |
49.2 ± 0.72 |
47.73 ± 0.50 |
48.2 ± 0.84 |
49.70 ± 1.21 |
0.3817 |
|
|
MC-Volume |
Fl |
65.6 ± 1.97 |
68.60 ± 0.37 |
66.63 ± 0.63 |
69.03 ± 0.40 |
0.1247 |
|
MC-Hemoglobin |
Pg |
21.9 ± 0.35 |
21.43 ± 0.41 |
21.23 ± 0.90 |
20.77 ± 0.51 |
0.5768 |
|
MCH-Concentration |
g/dl |
34.90 ± 0.39 |
34.73 ± 0.35 |
34.57 ± 0.27 |
35.5 ± 0.23 |
0.2242 |
|
Platelet |
103/µl |
918.7 ± 3.32 |
923.67 ± 2.95 |
924.33 ± 2.87 |
913.67 ± 3.17 |
0.1009 |
|
White Blood Cells |
103/µL |
5.67 ± 0.10 |
5.73 ± 0.08 |
5.73 ± 0.17 |
5.93 ± 0.13 |
0.5346 |
|
Neutrophils |
% |
23.70 ± 1.21 |
23.30 ± 1.69 |
20.17 ± 0.70 |
22.10 ± 0.13 |
0.1584 |
|
Lymphocytes |
% |
67.83 ± 3.81 |
69.73 ± 2.23 |
71.77 ± 2.44 |
68.5± 1.91 |
0.743 |
|
Monocytes |
% |
0.32 ± 0.01 |
0.36 ± 0.01 |
0.34 ± 0.00 |
0.32 ± 0.03 |
0.4033 |
|
Eosinophils |
% |
0.01 ± 0 |
0.01 ± 0 |
0.01 ± 0 |
0.01± 0 |
0 |
|
Basophils |
% |
0 ± 0 |
0 ± 0 |
0 ± 0 |
0 ± 0 |
0 |
All values are given as mean and standard error (SEM), each group had 4 rats and P value set at 0.05. MC- mean corpuscular, MCH - mean corpuscular hemoglobin