Table 5. Toxicity properties analysis of selected top three ligands’ through Admet SAR and Protox-III online server.
|
Properties |
Resveratrol (Control) |
CID 4970 (Protopine) |
CID 92782 (Gibberellin A7) |
CID 6466 (Gibberellic acid) |
|
Carcinogens |
No |
No |
No |
No |
|
Mutagenicity |
Inactive |
Active |
Inactive |
Inactive |
|
Cytotoxicity |
Inactive |
Inactive |
Inactive |
Inactive |
|
Hepatotoxicity |
Inactive |
Inactive |
Inactive |
Inactive |
|
LD50 (mg/kg) |
1560 |
940 |
6300 |
6300 |
|
Skin sensitisation |
No |
No |
No |
No |
|
Minnow toxicity (log mM) |
1.522 |
1.237 |
1.239 |
2.773 |
Control- Resveratrol.