Table 2. Effect of beetroot extract nanoparticle in ICAM-1 level in P. berghei-inoculated mice
Treatment |
ICAM-1 (ng/ml) level |
P value |
B |
200.21 (103.65-222.96) |
0.001 |
NC |
319.17 (254-334.34)* |
|
PC |
241.93 (224.68-262.62)# |
|
T1 (ART+NBE 50 mg) |
193.65 (135.72-256.41) # |
|
T2 (ART+NBE 100 mg) |
145.72(121.24-182.62)# |
|
T3 (ART+NBE 200 mg) |
151.24 (121.59-165.38)# |
B: Baseline, NC= negative control (inoculated with P. berghei), PC= positive control (inoculated with P. berghei + artemisinin 0.036 mg/g), T1= treatment 1(inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 50 mg/kg), T2= treatment 2 (inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 100 mg/kg), T3= treatment 3(inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 200 mg/kg). ART=artemisinin, NBE=nanoparticle of beetroot extract. Data is presented as median (n=5 for each group), when * p<0.05 compared to the baseline, and # p<0.05 compared to the negative control.