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Table 2. Effect of beetroot extract nanoparticle in ICAM-1 level in P. berghei-inoculated mice

Treatment

ICAM-1 (ng/ml) level

P value

B

200.21 (103.65-222.96)

0.001

NC

319.17 (254-334.34)*

PC

241.93 (224.68-262.62)#

T1 (ART+NBE 50 mg)

193.65 (135.72-256.41) #

T2 (ART+NBE 100 mg)

145.72(121.24-182.62)#

T3 (ART+NBE 200 mg)

151.24 (121.59-165.38)#

B: Baseline, NC= negative control (inoculated with P. berghei), PC= positive control (inoculated with P. berghei + artemisinin 0.036 mg/g), T1= treatment 1(inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 50 mg/kg), T2= treatment 2 (inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 100 mg/kg), T3= treatment 3(inoculated with P. berghei + artemisinin 0.036 mg/g+ nanoparticle of beetroot extract 200 mg/kg). ART=artemisinin, NBE=nanoparticle of beetroot extract. Data is presented as median (n=5 for each group), when * p<0.05 compared to the baseline, and # p<0.05 compared to the negative control.