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Table 2. Effect of C. maxima ethanol seed  extracts on levels of fasting blood glucose on alloxan-induced diabetes in rats.

 

 

 

Blood glucose levels (mmol/L)

 

 

Treatment

Baseline

0 h

2 h

4 h

6 h

24  h

Day 7

Day 14

Day 21

Day 28

Non-diabetic

 

5.12±0.20a

 

4.88±0.34b

 

4.94±0.27c

 

4.68±0.32c

 

5.04±0.28d

 

5.08±0.18d

 

5.06±0.29d

 

5.28±0.19c

 

5.20±0.19d

 

5.04±0.22d

Diabetic

 

5.20±0.21a

28.90±0.58a

29.16±0.74a

29.78±0.86a

29.48±0.43a

30.58±0.68a

30.08±0.71a

31.54±1.97a

29.42±0.75a

29.62±0.50a

Glibenclamide

 

5.20±0.23a

30.46±0.84a

25.14±0.35b

22.04±0.56b

19.92±0.34c

19.78±0.38c

13.28±0.54bc

13.06±0.55b

12.16±0.44b

11.89±0.30b

200mg/kg bw EtE

 

5.24±0.21a

29.04±0.39a

26.00±0.48b

23.54±0.38b

22.64±0.40b

22.02±0.30b

14.86±0.28b

12.68±0.20b

11.38±0.26bc

10.72±0.14bc

400mg/kg bw EtE

 

5.20±0.23a

29.56±0.67a

26.52±0.52b

22.64±0.33b

21.00±0.45c

18.34±0.32c

11.58±0.32c

10.16±0.25b

10.30±0.32c

10.14±0.25c

Using one-way ANOVA and Tukey's multiple comparisons, the means with mean±standard error that do not share a lowercase superscript letter along the column vary significantly (p<0.05). Non-diabetic = normal control; diabetic = alloxan treated-negative control; glibenclamide = reference drug treated to diabetic rats; EtE = ethanol extract treated to diabetic rats.