Table 1. Effect of C. maxima aqueous seed extract on levels of fasting blood glucose on alloxan-induced diabetes in rats.
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Blood glucose levels (mmol/L) |
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Treatment |
Baseline |
0 h |
2 h |
4 h |
6 h |
24 h |
Day 7 |
Day 14 |
Day 21 |
Day 28 |
Non-diabetic |
5.12±0.20a |
4.88±0.34b |
4.94±0.27c |
4.68±0.32d |
5.04±0.28e |
5.08±0.18d |
5.06±0.29e |
5.28±0.19d |
5.20±0.19e |
5.04±0.22d |
Diabetic |
5.20±0.21a |
28.90±0.58a |
29.16±0.74a |
29.78±0.86a |
29.48±0.43a |
30.58±0.68a |
30.08±0.71a |
31.54±1.97a |
29.42±0.75a |
29.62±0.50a |
5.20±0.23a |
30.46±0.84a |
25.14±0.35b |
22.04±0.56c |
19.92±0.34d |
19.78±0.38c |
13.28±0.54d |
13.06±0.55c |
12.16±0.44d |
11.89±0.30c |
|
200 mg/kg bw AqE |
5.32±0.28a |
29.64±0.36a |
28.80±0.44a |
27.94±0.38a |
26.56±0.33b |
25.00±0.26b |
21.84±0.37b |
19.06±0.35b |
18.44±0.44b |
15.14±0.34b |
400 mg/kg bw AqE |
5.24±0.25a |
29.82±0.31a |
27.78±0.23a |
25.10±0.41b |
23.12±0.28c |
19.74±0.35c |
17.22±0.28c |
15.30±0.33bc |
14.96±0.20c |
13.90±0.21b |
Using one-way ANOVA and Tukey's multiple comparisons, the means with mean±standard error that do not share a lowercase superscript letter along the column vary significantly (p<0.05). Non-diabetic = normal control; diabetic = alloxan treated-negative control; glibenclamide = reference drug treated to diabetic rats; AqE = aqueous extract treated to diabetic rats.