Polymorphisms in the leptin gene and their role in adolescent obesity and metabolic health

Table 4. Biochemical characteristics of the study participants.

Variables	Non-Obese (Mean ± SD)	Obese (Mean ± SD)	p^†
Total cholesterol (mg/dl) LDL (mg/dl) HDL (mg/dl) Triglycerides (mg/dl) Fasting blood glucose (mg/dl) Serum level of leptin (ng/mL) Serum level of insulin (µIU/ml) HOMA-IR	155.13 ± 37.92 105.60 ± 36.30 49.32 ± 7.80 82.56 ± 43.22 67.60 ± 5.59 6.39 ± 1.12 7.91 ± 6.96 1.33 ± 1.33	161.15 ± 32.56 110.60 ± 31.63 46.80 ± 7.97 113.72 ± 54.03 75.08 ± 21.70 11.57 ± 1.68 10.31 ± 7.78 2.02 ± 1.41	0.565 0.606 0.264 0.029* 0.102 0.000* 0.278 0.081

Variables

Non-Obese (Mean ± SD)

Obese (Mean ± SD)

p^†

Total cholesterol (mg/dl)

LDL (mg/dl)

HDL (mg/dl)

Triglycerides (mg/dl)

Fasting blood glucose (mg/dl)

Serum level of leptin (ng/mL)

Serum level of insulin (µIU/ml)

HOMA-IR

155.13 ± 37.92

105.60 ± 36.30

49.32 ± 7.80

82.56 ± 43.22

67.60 ± 5.59

6.39 ± 1.12

7.91 ± 6.96

1.33 ± 1.33

161.15 ± 32.56

110.60 ± 31.63

46.80 ± 7.97

113.72 ± 54.03

75.08 ± 21.70

11.57 ± 1.68

10.31 ± 7.78

2.02 ± 1.41

0.565

0.606

0.264

0.029*

0.102

0.000*

0.278

0.081

*Reached statistical significance (p < 0.05); ^†Independent T-Test; LDL: low-density lipoprotein; HDL: high-density of lipoproteins; HOMA-IR: homeostasis model assessment for insulin resistance