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Table 1. Summary of the experimental groups.

Experimental groups

Duration

Control (Distilled H2O considered as normal control)

21 days

ACP (ACP 300 mg/kg bw IP on 18th day considered as negative control)

21 days

ACP+Sily (Sily 25 mg/kg bw + ACP 300 mg/kg bw IP on 18th day; positive control)

21 days

ACP+SVE30 (SVE 30 mg/kg bw + ACP 300 mg/kg bw IP on 18th day)

21 days

ACP+SVE100 (SVE 100 mg/kg bw) + ACP 300 mg/k bw IP on 18th day)

21 days

ACP+SVE300 (SVE 300 mg/kg bw + ACP 300 mg/kg bw IP on 18th day)

21 days

ACP+SVE500 (SVE 500mg/kg bw + ACP 300 mg/kg bw IP on 18th day)

21 days

Kg bw = kilogram body weight; ACP = acetaminophen and Sily = Silymarin and IP= intraperitoneal, and SVE=S. villosum leaf methanol extracts.