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Table 3. Significantly altered metabolites in non-diabetic participants following RDIF.

m/z Ratio

Fold Change

Direction of change

P-value

KEGG ID

Name of Metabolites

Formula

782.1

2.8605

Elevated

0.013158

C00083

Malonyl coenzyme A

C24H38N7O19P3S

217.1

4.0485

Elevated

0.017885

C00120

Biotin (Coenzyme R)

C10H16N2O3S

568.1

2.7272

Elevated

0.02218

C11583

4-Glutathionyl cyclophosphamide

C17H30Cl2N5O8PS

441

2.2516

Elevated

0.03017

C00081

Inosine 5'-triphosphate

C10H15N4O14P3

397.2

0.10644

Reduced

0.003117

C04717

13S-Hydroperoxy-9Z,11E-octadecadienoic acid

C18H32O4

372.2

0.207

Reduced

0.006399

C00445

5,10-Methenyltetrahydrofolate

C20H22N7O6

701.1

0.3738

Reduced

0.049228

C00006

Nicotinamide adenine dinucleotide phosphate (NADP+)

C21H29N7O17P3

415.1

0.51669

Reduced

0.004846

C00255

Riboflavin

C17H20N4O6

371.2

0.51976

Reduced

0.004714

C05011

4-Hydroxytamoxifen

C26H29NO2

C16545

Tamoxifen N-oxide

C26H29NO2

C16544

alpha-Hydroxytamoxifen

C26H29NO2

C00473

Retinol (Vitamin A)

C20H30O

C16682

9-cis-Retinol

C20H30O

C00899

11-cis-Retinol

C20H30O

272.2

0.52537

Reduced

0.004521

C01137

S-Adenosylmethioninamine

C14H23N6O3S

Ramadan Diurnal Intermittent Fasting (RDIF)