mtDNA Alterations

Nature Variant

Overview

Ref.

4399–14821 Deletion

Heteroplasmic

Deletion associated with maternal inheritance of  DM and deafness

[57]

A3243G

Heteroplasmic

Variant associated with T2DM

[58]

T14577C

Heteroplasmic

Variant associated with T2DM

[59]

T16189C

Mostly Homoplasmic

Variant associated with T2DM

[60]

A5178C

N/A

Variant associated with maternally inherited T2DM

[61]

C8684T

N/A

Variant associated with T2DM

[62]

T4216C, A4917G

Homoplasmic

Variants associated with T2DM

[63]

16189–16193 Polycytosine Variant

N/A

Variant associated with T2DM

[64]

G3316A, T3394C

N/A

Variants associated with T2DM

[65]