Effect of Gynura procumbens leaf extract with biological nanoparticles on streptozotocin-induced hyperglycemia in a rat model

Table 2. Effect of Gynura procumbens plant extracts and Chitosan Nanoparticles on biochemical parameters in streptozotocin-induced diabetics rats.

Treatment	Insulin µU/ml	ALT U/L	AST U/L
T0	.3450±.04444^a	181.50±14.402^b	139.00±4.509^b
T1	.1725±.02136^b	463.75±72.765^a	322.00±69.862^a
T2	.2850±.02217^ab	295.25±67.492^ab	225.75±26.952^ab
T3	.4125±.03902^a	237.00±28.428^b	165.50±12.790^ab
P- value	0.002***	0.013***	0.024***

Values with the different superscripts in the same column are statistically significant at (p<0.05) Here *** denotes 5% level of significance. Figures indicate the Mean ± SE (standard Error). T0 = control (normal), T1 = streptozotocin (60 mg/kg body weight)-induced diabetes, T2 =streptozotocin-induced diabetes treated with ethanolic extract of Gynura Procumbens (150 mg/kg body weight), and T3= streptozotocin induced diabetes treated with ethanolic extract of Gynura Procumbens (150 mg/kg) and chitosan nanoparticles (25 mg/kg).