Effect of Gynura procumbens leaf extract with biological nanoparticles on streptozotocin-induced hyperglycemia in a rat model

Table 1. Effect of Gynura procumbens plant extracts and Chitosan Nanoparticles on blood glucose level in streptozotocin-induced diabetic rats.

Treatment	7 Days	14 Days	21 days
T0	5.1250±.26260^b	7.0250±.72154^c	5.7750±.30653^c
T1	30.4250±1.83456^a	30.2000±1.98452^a	26.2750±1.76889^a
T2	25.9250±2.41674^a	25.4250±1.95379^a	18.3250±.71575^b
T3	26.3500±2.34183^a	18.0250±1.54616^b	15.4500±1.33760^b
P- value	0.000***	0.000***	0.000***

Blood glucose level (mmol/L, mean±SE) in streptozotocin induced diabetic rats. n=4 at seven days interval after treatment. Values with the different superscripts in the same column are statistically significant at (p<0.01) Here *** denotes 1% level of significance. Figures indicate the Mean ± SE (standard Error). T0 = control (normal), T1 = streptozotocin (60 mg/kg body weight)-induced diabetes, T2 =streptozotocin-induced diabetes treated with ethanolic extract of Gynura Procumbens (150 mg/kg body weight), and T3= streptozotocin induced diabetes treated with ethanolic extract of Gynura Procumbens (150 mg/kg) and chitosan nanoparticles (25 mg/kg).