Table 6. Association between ERCC2 polymorphisms and clinicopathological features of CRC.
|
Clinicopathologic characteristics |
rs238406 |
rs1799793 |
||
|
CC |
AC+AA |
AA |
GA+GG |
|
|
Tumor location: Colon |
19 |
32 |
6 |
45 |
|
Rectum |
13 |
14 |
6 |
21 |
|
P value |
0.381 |
0.221 |
||
|
Tumor differentiation Well |
5 |
9 |
1 |
13 |
|
Moderate |
16 |
28 |
8 |
37 |
|
Poor |
8 |
6 |
2 |
12 |
|
P value |
0.36 1 |
0.62 2 |
||
|
Grade: II |
17 |
17 |
6 |
27 |
|
III and IV |
15 |
29 |
6 |
39 |
|
P value |
0.15 1 |
0.34 1 |
||
|
Tumor invasion T1 and T2 |
7 |
7 |
3 |
11 |
|
T3 and T4 |
25 |
39 |
9 |
55 |
|
P value |
0.45 1 |
0.44 2 |
||
|
Lymph node involvement N0 |
16 |
15 |
6 |
26 |
|
N1 and N2 |
16 |
31 |
6 |
40 |
|
P value |
0.12 1 |
0.49 1 |
||
1chi square test was used, and 2Fisher exact test was used.