Table 2. Associations between genetic abnormality status and patient characteristics.
|
EGFR mutation |
ALK mutation |
ROS1 mutation |
RET mutation |
MET mutation |
||||||||||||||
|
Yes |
% |
p-value |
Yes |
% |
p-value |
Yes |
% |
p-value |
Yes |
% |
p-value |
Yes |
% |
p-value |
|
|||
|
179 |
73 |
40.8 |
|
18 |
10.1 |
|
8 |
4.5 |
|
5 |
2.8 |
|
4 |
2.2 |
|
|
||
|
Age |
|
|
0.267 |
|
|
0.328 |
|
|
0.470 |
|
|
1.000 |
|
|
0.629 |
|
||
|
≤ 60 |
80 |
29 |
36.2 |
|
10 |
12.5 |
|
3 |
6.2 |
|
2 |
2.5 |
|
1 |
1.2 |
|
|
|
|
> 60 |
99 |
44 |
44.4 |
|
8 |
8.1 |
|
5 |
3.0 |
|
3 |
3.0 |
|
3 |
3.0 |
|
|
|
|
Gender |
|
|
0.010 |
|
|
0.972 |
|
|
0.117 |
|
|
1.000 |
|
|
1.000 |
|
||
|
Male |
120 |
41 |
34.2 |
|
12 |
10.0 |
|
3 |
2.5 |
|
4 |
3.3 |
|
3 |
2.5 |
|
|
|
|
Female |
59 |
32 |
54.2 |
|
6 |
10.2 |
|
5 |
8.5 |
|
1 |
1.7 |
|
1 |
1.7 |
|
|
|
|
Tumor site |
|
|
0.049 |
|
|
0.032 |
|
|
0.096 |
|
|
1.000 |
|
|
0.244 |
|
||
|
Primary |
136 |
61 |
44.9 |
|
10 |
7.4 |
|
4 |
2.9 |
|
4 |
2.9 |
|
2 |
1.5 |
|
|
|
|
Metastasis |
43 |
12 |
27.9 |
|
8 |
18.6 |
|
4 |
9.3 |
|
1 |
2.3 |
|
2 |
3.7 |
|
|
|
|
Smocking status |
|
|
0.014 |
|
|
0.409 |
|
|
0.114 |
|
|
0.165 |
|
|
0.313 |
|
||
|
Yes |
76 |
23 |
30.3 |
|
6 |
7.9 |
|
1 |
1.3 |
|
4 |
5.3 |
|
3 |
3.9 |
|
|
|
|
No |
103 |
50 |
48.5 |
|
12 |
11.7 |
|
7 |
6.8 |
|
1 |
1.0 |
|
1 |
1.0 |
|
|
|
|
Stages |
|
|
|
0.151 |
|
|
0.049 |
|
|
0.959 |
|
|
0.630 |
|
|
|
|
|
|
|
I-II |
29 |
16 |
55.2 |
|
0 |
0.0 |
|
1 |
3.4 |
|
0 |
0.0 |
|
0 |
0.0 |
0.394 |
|
|
|
III |
64 |
27 |
42.2 |
|
5 |
7.8 |
|
3 |
4.7 |
|
2 |
3.1 |
|
1 |
1.6 |
|
|
|
|
IV |
86 |
30 |
34.9 |
|
13 |
15.1 |
|
4 |
4.7 |
|
3 |
3.5 |
|
3 |
3.5 |
|
|