Groups

Treatment

Time (seconds)

Day 1

Day 2

Day 3

Group A (Normal control)

Normal saline

236.67±6.91^a

272.37±5.81^a

276.05±5.06^a

Group B (Negative control mice)

Ketamine (15mg/kg bw) + Normal saline

130.16±6.17^d

130.16±5.59^c

67.22±5.22^e

Group C (Positive control mice)

Ketamine (15mg/kg bw) + Donepezil (1mg/kg bw)

154.45±4.96^c

132.9±4.64^c

154.4±7.13^d

Group D (Experimental group)

Ketamine (15mg/kg bw) + 200 mg/kg bw

206.69±6.81^ab

257.98±5.97^a

243.04±4.72^b

Group E (Experimental group)

Ketamine (15mg/kg bw) + 300 mg/kg bw

160.19±5.66^c

136.64±6.22^c

160.19±7.84^d

Group F (Experimental group)

Ketamine (15mg/kg bw) + 400 mg/kg bw

200.89±7.9^b

196.69±4.63^b

192.74±6.04^c