Assessment of antiproliferative and toxic effects of a peptide from Momordica dioica using in vitro and in vivo studies

Table 1. Behavioral responses and general parameters observed in mice treated with different doses of peptide.

Groups	Bodyweight (g)	Rectal bleeding observation	Stool observation	Animal behavior observation	Secretion
GI (Control group)	25.5 ± 1.2	Not observed	Normal	Normal	Not observed
GII (50 mg/kg BW)	26.16 ± 1.76	Not observed	Normal	Normal	Not observed
GIII (100mg/kg BW)	29.05 ± 1.15	Not observed	Normal	Normal	Not observed
GIV (150mg/kg BW)	27.07 ± 1.83	Not observed	Normal	Normal	Not observed
GV (200mg/kg BW)	29.76 ± 3.84	Not observed	Normal	Normal	Not observed
GVI (250mg/kg BW)	24.02 ± 1.22^a	Not observed	Normal	Normal	Not observed
The significant difference (P<0.05) was represented as ^acompared with peptide treatment and control group according to Dunnett test.