Table 2. Effect of metformin on antioxidant and oxidant status in both PCOS patients and control group according to the plasma and erythrocytes.
|
Oxidant and antioxidant criteria |
Patients without metformin |
Patient with metformin |
P-value |
|
|
Cu/zn SOD |
Plasma |
64.58 ± 6.363 |
45.47 ± 4.835* |
0.0196 |
|
Erythrocyte |
26.27 ± 2.88 |
17.86 ± 2.849* |
0.0450 |
|
|
TAC
|
Plasma |
1764 ± 462.7 |
800.1 ± 130.4* |
0.0486 |
|
Erythrocyte |
1103 ± 31.5 |
1063 ± 27.43 |
0.3431 |
|
|
TOS
|
Plasma |
37.32 ± 2.122 |
30.98 ± 1.82* |
|
|
Erythrocyte |
54.36 ± 2.724 |
45.2 ± 1.785** |
0.0050 |
|
* Significant difference (P ≤0.05) and **Significant difference (P ≤0.01).