Determining the disease outcome by cytokine storm during infectious diseases and targeting cytokines during sepsis: Possible therapeutic options

Table 1. Sepsis animal model.

Pharmacological agents	Animals used	Challenges	Results	Ref.
BN 5021	Mouse	Intravenous LPS	Positive	[83]
TAK-242	Mouse	Intraperitoneal LPS	Positive	[84]
Tifacogin	Baboon	Viable intravenous E. coli	Positive	[85]
BB-882	Mouse	Intravenous LPS	Positive	[86]
Tifacogin	Mouse	Cecal ligation and puncture (CLP)	Positive	[87]
IL1-RA	Mouse	Intraperitoneal LPS	Positive	[88]
Methylprednisolone sodium succinate	Baboon	Viable intravenous E. coli	Positive	[89]
Lenercept	Baboon	Viable intravenous E. coli	Positive	[90]
Tifacogin	Rabbit	Peritonitis caused by E. coli 018: K+	Positive	[91]
CDP571	Baboon	Viable intravenous E. coli	Positive	[92]