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Table 9. Association of rs4889 genotypes with PCOS under different models of inheritance.

Model

Genotype

Control

(No.60)

Patient

(No.60)

Odd ratio

(95% CI)

P. Value

Co. dominant

GG

65% (n=39)

22%(n=13)

References (OR=1)

GA

33% (n=20)

51%(n=31)

4.65 (2.0 to 10.8)

0.0004

AA

1.6% (n=1)

27% (n=16)

48 (5.8 to 398.1)

0.0003

dominant

GG

65% (n=39)

22%(n=13)

References (OR=1)

 

0.0001

GA-AA

35% (n=21)

78% (n=47

6.7143(2.9822 to 15.11)

Recessive

 

GG-GA

%98 (n=59)

73% (n=44

References (OR=1)

 

0.0035

AA

1.6% (n=1)

27% (n=16

21.5 (2.7 to 167.94)

Over dominant

AA-GG

67% (n=40)

49% (n=29

References (OR=1)

 

0.04

GA

33% (n=20)

51%(n=31)

2.14 (1.02 to 4.47)