Table 7. Association of rs372790354 genotypes with PCOS under different models of inheritance.
Model |
Genotype |
Control (No.60) |
Patient (No.60) |
Odd ratio (95% CI) |
P. Value |
Codominant |
GG |
58% (n=35) |
30% (n=18)
|
References (OR=1) |
|
GA |
40% (n=24) |
50% (n=30) |
2.4 (1.1 to 5.3) |
0.026 |
|
AA |
1.6% (n=1) |
20% (n=12) |
23.3 (2.8 to 193.9.3) |
0.0036 |
|
dominant |
GG |
58% (n=35) |
30% (n=18) |
References (OR=1) |
0.0021 |
GA-AA |
41% (n=25) |
70% (n=42) |
3.2667 (1.537 to 6.942) |
||
Recessive
|
GG-GA |
98% (n=59) |
80% (n=48) |
References (OR=1) |
0.011 |
AA |
1.6% (n=1) |
20% (n=12) |
14.7 (1.85 to 117.5) |
||
Over dominant |
AA-GG |
60% (n=36) |
50% (n=30) |
References (OR=1) |
0.27 |
GA |
40% (n=24) |
50% (n=30) |
1.50 (0.73 to 3.1) |