Table 14. Genotype combination of SNPs rs4889 and rs372790354 in KISS1 gene between patient group and control group (Allele Frequencies detected by Hardy-Weinberg equilibrium law).
|
rs4889 + rs372790354 |
Control (No.60) |
Patient (No.60) |
Odd ratio (95% CI) |
P. Value |
|
Normal/Normal GG+GG |
24 |
5 |
References (OR=1) |
|
|
Normal/Hetero GG+GA |
14 |
6 |
1.05 0.5 to 7.9 |
0.29 |
|
Normal/Mutant GG+AA |
1 |
2 |
9.6 0.7 to 127.5 |
0.086 |
|
Hetero/Normal GA+GG |
11 |
8 |
3.49 0.92 to 13.1 |
0.064 |
|
Hetero/Hetero GA+GA |
9 |
18 |
9.6 2.74 to 33.5 |
0.0004 |
|
Hetero/Mutant GA+AA |
0 |
5 |
49.0 2.3 to 1023.57 |
0.0121 |
|
Mutant/Normal AA+GG |
0 |
5 |
49.0 2.3 to 1023.57 |
0.0121 |
|
Mutant/Hetero AA+GA |
1 |
6 |
28.8 2.8 to 294.8 |
0.0046 |
|
Mutant/Mutant AA+AA |
0 |
5 |
49.0 2.3 to 1023.57 |
0.0121 |
*Significant differences at P-Value ≤ 0.05