Table 12. The influence of rs4889 G>A polymorphism of KISS1 gene on the mean difference of characteristics and parameters between genotypes normal weight (patient and control) group.
|
Parameter
|
Group
|
Genotype of rs4889 |
(P-value) |
|
|
GA Mean ±SE |
AA Mean ±SE |
|||
|
No. |
PCOS Patients |
18 |
9 |
|
|
control |
8 |
1 |
|
|
|
WHR |
PCOS Patients |
0.89 ±0.01 |
0.9 ±0.02 |
GA<0.01 AA=0.09 |
|
Control |
0.81±0.01 |
0.77 |
||
|
LH (mIU/ml) |
PCOS Patients |
8.79 ±1.11 |
11.58±3.1 |
GA=0.19 AA=0.4 |
|
control |
6.26±1.3 |
3.2 |
||
|
FSH (mIU/ml) |
PCOS Patients |
6.06±1.6 |
3.8±0.43 |
GA=0.35 AA=0.52 |
|
control |
8.59±1.48 |
4.8 |
||
|
LH/FSH Ratio |
PCOS Patients |
2.11±0.28 |
3.18±0.77 |
GA<0.01 AA=0.33 |
|
control |
0.81±0.04 |
0.66 |
||
|
kisspeptin ng/L |
PCOS Patients |
300.4±38.3 |
1062±187 |
GA=0.2 AA=0.19 |
|
control |
363.7±20 |
220.1 |
||
|
F.Testosterone (pg/ml) |
PCOS Patients |
2.16±0.17 |
1.98±0.31 |
GA<0.01 AA=0.34 |
|
control |
0.81±0.04 |
1.0 |
||
|
DHEA-S (μg/dl) |
PCOS Patients |
312.9±35.3 |
402±67.4 |
GA<0.01 AA=0.42 |
|
Control |
175±22.6 |
224 |
||
*Significant differences at P-Value ≤ 0.05