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Table 4. The frequency of different genotypes and allele of rs7144366 in hepatitis patients with and without HCC.

rs7144366

Without HCC

(n=45)

With HCC

(n=40)

P-value

OR (95%CI)

Genotypes

TT

CT

CC

HWE

 

19(42.22%)

20(44.44%)

6(13.33%)

0.839

 

15(37.5%)

14(35%)

11(27.5%)

0.064

 

0.270

0.806

0.170

 

1.0

0.89(0.34-2.32)

2.32(0.7-7.73)

Dominant models

TT+CT

CC

 

Recessive model

TT

CT+CC

 

39(86.67%)

6(13.33%)

 

 

19(42.22%)

26(57.78%)

 

29(72.5%)

11(27.5%)

 

 

15(37.5%)

25(62.5%)

 

0.109

 

 

 

0.576

 

1.0

2.47(0.82-7.44)

 

 

1.0

1.22(0.51-2.91)

Alleles

T

C

 

58(64.44%)

32(35.56%)

 

44(55%)

36(45%)

 

0.210

 

1.0

1.48(0.8-2.75)