Table 1. Effect of ramipril treatment on body weight, food and water intake and organ weights in alloxan-induced diabetes rats.
|
Parameters |
Control |
Control + Ramipril |
Alloxan |
Alloxan + Ramipril |
|
Initial Body weight (g) |
183.58±.82 |
166.63±4.63 |
182.92±.82 |
192.38±4.84 |
|
Final Body weight (g) |
237.98±1.80 |
221.85±4.08 |
200.87±7.28 |
239.22±3.50 |
|
Food intake/d (g) |
19.46±0.20 |
17.76±0.22 |
19.50±0.20 |
18.91±0.23 |
|
Water intake/d (g) |
19.91±0.24 |
22.51±0.31 |
21.04±0.11 |
24.01±0.41 |
|
Liver wet weight (g/100 g of body weight) |
3.41±0.19a |
3.09±0.10a |
3.88±0.22b |
3.93±0.15b |
|
Kidneys wet weight (g/100 g of body weight) |
0.62±0.03a |
0.62±0.05a |
0.82±0.22b |
0.70±0.03b |
|
Heart wet weight (g/100 g of body weight) |
0.26±0.01 |
0.31±0.01 |
0.30±0.01 |
0.32±0.01 |
|
Spleen wet weight (g/100 g of body weight) |
0.30±0.02 |
0.33±0.02 |
0.40±0.04 |
0.37±0.03 |
|
Pancreas wet weight (g/100 g of body weight) |
0.23±0.01a
|
0.24±0.02a
|
0.38±0.04b
|
0.30±0.01b
|
Values are presented as mean±SEM. N=5-6 in each group or otherwise specified. One way ANOVA with Newman-Keuls tests were done as post hoc test. Values are considered significance at p<0.05.