Study on relationship between genetic abnormalities and clinicopathological features in K hospital’s patients with colorectal cancer

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Table 4. Correlation with regards to KRAS, NRAS, BRAF and PIK3CA abnormalities in CRC

			*NRAS* mutation		p- *value*	*BRAF* mutation		*p-value*	*PIK3CA mutation*		*p-value*	**RAS/RAF mutations**		*p-value*
			Yes	No	p- *value*	Yes	No	*p-value*	Yes	No	*p-value*	Yes	No	*p-value*
N		251	18	233		16	235		44	207		120	131
KRAS mutation					0.001			0.003			0.002
	Yes	86	0	86		0	86		24	62
	No	165	18	147		16	149		20	145
NRAS mutation								0.251			0.457
	Yes	18				0	18		2	16
	No	233				16	217		42	191
PIK3CA mutation								0.894						0.008
	Yes	44				3	41					29	15
	No	207				13	194					91	116

χ² test; Fisher’s extract test