Group

Treatment

Percent inhibition of pain after treatment

Early phase

Late phase

Negative control 

DMSO 5%  

100.00±0.00^a

 100.00±0.00^a

Normal control

Formalin 2.5%

0.00±0.00^d

 0.00±0.00^e

Positive control

Formalin 2.5% + Paracetamol (50mg/kg bw)

67.75±2.80^bc

56.84±1.30^b

Experimental groups

A

 Formalin + C. pareira (50mg/kg bw)

62.12±2.76^c   

42.41±4.01^c           

B

 Formalin + C. pareira (100mg/kg bw)

73.72±1.79^bc    

62.05±3.18^b           

C

 Formalin + C. pareira (150mg/kg bw)

79.89±1.41^b

29.59±1.43^cd          

D

 Formalin + C. pareira (200mg/kg bw)

71.43±4.87^bc 

28.57±4.36^d            

E

 Formalin + C. pareira (250mg/kg bw)

64.73±6.97^bc

21.69±4.56^d

Values are expressed as Mean ± SEM. Statistical comparison was made within a column. Values with the same superscript are not significantly different (p>0.05).