Group

Treatment

Percent inhibition of pain after treatment

Early phase

Late phase

Negative control 

DMSO 5%  

100.00±0.00^a

100.00±0.00^a

Normal control

Formalin 2.5%

0.00±0.00^d

0.00±0.00^c

Positive control

Formalin 2.5% + Paracetamol (50mg/kg bw)

45.79±1.68^c

41.79 ±1.51^b

Experimental groups

A

 Formalin + C. pareira (50mg/kg bw)

52.03±3.18^bc

34.22±5.73^b

B

 Formalin + C. pareira (100mg/kg bw)

67.02±4.20^b

41.27±5.34^b

C

 Formalin + C. pareira (150mg/kg bw)

53.26±4.16^bc

36.51±6.83^b

D

 Formalin + C. pareira (200mg/kg bw)

51.85±5.50^bc

27.16±7.53^b

E

 Formalin + C. pareira (250mg/kg bw)

39.86±6.90^c

22.05±7.88^bc

Values are expressed as Mean ± SEM. Statistical comparison was made within a column. Values with the same superscript are not significantly different (p>0.05).