Group

Treatment

Percent inhibition of pain after treatment

Early phase

Late phase

Negative control 

DMSO 5%  

0.00±0.00^d

0.00±0.00^d

Normal control

Formalin 2.5%

100.00±0.00^a

100.00±0.00^a

Positive control

Formalin 2.5% + Paracetamol (50mg/kg bw)

67.75±2.80^b

56.84±1.30^b             

Experimental groups

A

 Formalin + C. pareira (50mg/kg bw)

59.73±3.65^b

16.23±3.84^cd

B

 Formalin + C. pareira (100mg/kg bw)

70.90±2.48^b

64.90±5.43^b

C

 Formalin + C. pareira (150mg/kg bw)

64.73±2.57^b

49.03±9.71^b

D

 Formalin + C. pareira (200mg/kg bw)

40.21±3.39^c

27.60±1.55^c         

E

 Formalin + C. pareira (250mg/kg bw)

35.98±2.85^c

22.81±1.98^c            

Values are expressed as Mean ± SEM. Statistical comparison was made within a column. Values with the same superscript are not significantly different (p>0.05).