Group

Treatment

Percent inhibition of pain after treatment

Early phase

Late phase

Normal control          

DMSO 5%  

100.00±0.00^a

100.00±0.00^a

Negative control

Formalin 2.5%

0.00±0.00^e

0.00±0.00^d

Positive control

Formalin 2.5% + Paracetamol (50mg/kg bw)

45.79±1.68^bcd

41.79±1.51^b

Experimental groups

A

 Formalin + C. pareira (50mg/kg bw)

38.45±7.62^cd

27.51±6.71^bc

B

 Formalin + C. pareira (100mg/kg bw)

44.80±4.16^bcd

37.22±6.80^b

C

 Formalin + C. pareira (150mg/kg bw)

61.02±4.47^b

40.92±5.71^b

D

 Formalin + C. pareira (200mg/kg bw)

55.73±6.95^bc

26.63±5.10^bc

E

 Formalin + C. pareira (250mg/kg bw)

31.75±2.34^d

10.68±1.71^cd

Values are expressed as Mean ± SEM. Statistical comparison was made within a column. Values with the same superscript are not significantly different (p>0.05).