Table 4. MHC-I associated antigenic peptide predicted on the spike glycoprotein.
|
Peptide |
VaxiJen |
IFN-γ Response |
CTLPred Score (ANN/SVM) |
MHC Restriction |
|
174- YFPLQSYGF-182 |
Antigen (0.5107) |
Negative (-0.2288) |
- |
HLA-A*24:02, HLA-A*23:01 |
|
102- KIADYNYKL- 110 |
Antigen (1.6639) |
Negative (-0.3740) |
0.72/0.74005 (Epitope) |
HLA-A*02:01, HLA-A*02:06, HLA-A*32:01, HLA-A*02:03 |
|
71- KLNDLCFTNV- 80 |
Antigen (2.6927) |
Negative (-0.8044) |
0.03/0.67438 (Epitope) |
HLA-A*02:03, HLA-A*02:01 |
|
93-RQIAPGQTGK-102 |
Antigen (1.7893) |
Negative (-0.1924) |
0.48/0.83303 (Epitope) |
HLA-A*03:01 |
|
125 -NLDSKVGGNY -134 |
Antigen (0.7882) |
Negative (-0.1738) |
0.02/0.1194 (Non-epitope) |
HLA-A*01:01 |
|
143 -KSNLKPFER - 151 |
Antigen (0.9490) |
Negative (-0.3191) |
0.82/1.07575 (Epitope) |
HLA-A*31:01 |
|
34 -SVYAWNRKR -42 |
Antigen (0.7650) |
Positive (0.2458) |
0.27/0.15625343 (Non-epitope) |
HLA-A*31:01, HLA-A*68:01 |
|
192 -PYRVVVLSF - 200 |
Antigen (1.0281)c |
Negative (-0.018) |
0.49/0.10768 (Non-epitope) |
HLA-A*23:01, HLA-A*24:02 |
|
29-ATRFASVYA -38 |
Antigen (0.0785) |
Negative (-0.020) |
0.86/0.24604 (Epitope) |
HLA-A*30:01, HLA-B*58:01, HLA-B*57:01 |
|
98- GQTGKIADY -108 |
Antigen (1.4019) |
Negative (-0.206) |
- |
HLA-B*15:01, HLA-A*01:01 |
|
200- FELLHAPATV-209 |
Antigen (0.5982) |
Negative (-0.135) |
0.00/0.84172 (Epitope) |
HLA-A*02:03 |
|
129 -KVGGNYNYLY- 138 |
Antigen (0.5338) |
Positive (0.393) |
1.00/1.07922 (Epitope) |
HLA-A*30:02 |