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Table 3. Predicted antigenic B-cell linear epitopes found in the spike glycoprotein with their antigenic scores, VaxiJen scores, and IFN-γ responses.

Sequence

Start Position

Score

VaxiJen

Score

IFN-γ

Response

LQSYGFQPTNGVGYQP

177

0.90

Antigen (0.5258)

Positive (14)

EVRQIAPGQTGKIADY

91

0.85

Antigen (1.3837)

Negative (1)

TGKIADYNYKLPDDFT

100

0.84

Antigen  (0.9642)

Negative (-0.334)

FPNITNLCPFGEVFNA

14

0.82

Antigen(0.6058)

Negative (-0.138)

VQPTESIVRFPNITNL

5

0.80

Antigen (0.4454)

Positive (7)

NGVGYQPYRVVVLSFE

186

0.77

Antigen (0.9736)

Positive (0.371)

FSTFKCYGVSPTKLND

59

0.76

Antigen (0.9650)

Positive (1)

EGFNCYFPLQSYGFQP

169

0.73

Antigen (0.6870)

Positive (0.0261)

TGCVIAWNSNNLDSKV

115

0.71

Antigen (0.5086)

Positive (0.101)

FVIRGDEVRQIAPGQT

85

0.69

Antigen (0.5147)

Positive (2)

VVLSFELLHAPATVCG

196

0.66

Antigen (0.6184)

Positive (0.395)

RKSNLKPFERDISTEI

142

0.65

Antigen (0.4298)

Positive (0.332)

PTKLNDLCFTNVYADS

69

0.62

Antigen (1.2303)

Negative (-0.426)