Table 1. The effect of methanolic extract of H. coccineum leaves on castor oil induced diarrhea in Swiss albino mice.
|
Treatment (mg/kg) |
Total number of feces |
Inhibition of defecation (%) |
Total number of diarrheal feces |
Inhibition of diarrhea (%) |
|
Negative Control (0.1 mL/mice) |
14.60 ± 0.46 |
- |
6.40 ± 0.47 |
- |
|
Loperamide (5) |
5.40 ± 0.14 d |
63.01 |
2.20 ± 0.12 d |
65.63 |
|
MEHCL 200 |
10.00 ± 2.73 |
31.51 |
3.67 ± 0.88 a |
42.71 |
|
MEHCL 400 |
6.67 ± 1.26 c |
54.31 |
3.00 ± 0.38 c |
53.12 |
Results represented in Mean ± SEM (n=5). a P < 0.05, c P < 0.001 and d P < 0.0001 are statistically significant in comparison to Tween-80 (Control) followed by unpaired t-test of one-way ANOVA (GraphPad Prism 7).