Table 1. ACE inhibition and Kinetic Parameters by MOLME.
|
|
Kinetic parametersa |
|
Compound |
IC50b |
Vmax (OD/30 min) |
Km (mM) |
no inhibitor |
- |
0.0857 |
4.671 |
MOLME |
226.37±0.021 μg/ml |
0.0541 |
4.41 |
CP |
0.0289±0.011 μM |
0.0857 |
17.52 |
a Kinetic parameter was calculated from Fig. 3b. IC50 was calculated from Fig. 1 and 2.