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Table 1:  Recommended antiretroviral regimen for initial therapy. 

Recommended regimen for HIV treatment

INSTI + 2 NRTIs:

-DTG/ABC/3TC or FTC (AI)—if HLA-B*5701 negative

-DTG + tenofovir/FTC or 3TC (AI for both TAF/FTC and TDF/FTC)

-EVG/c/tenofovir/FTC (AI for both TAF/FTC and TDF/FTC)

-RAL + tenofovir/FTC or 3TC (AI for TDF/FTC, AII for TAF/FTC)

Abbreviations: 3TC, lamivudine; ABC, abacavir; DTG, dolutegravir; EVG, elvitegravir; EVG/c,  elvitegravir/cobicistat; FTC, emtricitabine; HLA, human leukocyte antigen; INSTI, integrase strand transfer inhibitor; NRTI, nucleoside reverse transcriptase inhibitor; RAL, raltegravir; RPV, rilpivirine; TAF, tenofovir alafenamide; TDF, tenofovir disoproxil fumarate.